Required: Men's TRT Initial Panel (Quest)
Essential testing for safe and effective testosterone therapy.
$149 one-time
Add to cart- Prescribed by a licensed clinician, when appropriate
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The Required: Men's TRT Initial Panel provides a targeted assessment of key hormones and safety markers necessary for initiating testosterone therapy. Testosterone replacement requires careful monitoring to ensure therapy is appropriate, effective, and safe over time. This panel evaluates testosterone levels alongside pituitary signaling, thyroid function, and prostate-related markers to provide clinical context for treatment decisions. It is required within six months prior to starting testosterone therapy (including testosterone injections, testosterone cream, hCG, and enclomiphene) to evaluate eligibility. Sample type: serum.
What it may help with
Baseline hormones: measures total and free testosterone plus related hormone markers
Safety screening: checks blood counts, metabolic markers, and PSA where appropriate
A precise starting point: gives your clinician the data to build your protocol
What this panel evaluates
Comprehensive metabolic panel (CMP)
Includes fasting glucose and markers of liver, kidney, and electrolyte balance
CBC with differential
Offers context on overall health and inflammatory or physiologic stress
Total testosterone
Measures overall testosterone levels
Free testosterone
Assesses biologically active testosterone
Estradiol
Evaluates estrogen balance and conversion, which can influence symptoms and treatment response
LH and FSH
Luteinizing hormone and follicle stimulating hormone assess pituitary signaling to the testes
Thyroid function
TSH and free T4 to assess metabolic regulation
Prolactin
Assesses for hormonal influences that may suppress testosterone
Total + Free PSA
Prostate specific antigen screens prostate health for men
Sex Hormone-Binding Globulin (SHBG)
Assesses biologically active hormone levels
Adrenal and stress hormones
Urinary cortisol (AM) to evaluate stress response patterns
Androgen support
DHEA-S as a marker of adrenal reserve and resilience
Ferritin
Reflects iron storage and acts as an acute phase reactant in inflammatory states
What to expect
After purchase you'll receive a lab requisition. Visit any Quest location at your convenience; results typically return within a few business days and are reviewed by your clinician before any prescription is issued. It is recommended to fast for at least 8 hours before your draw.
How it works
Order the panel
The Required: Men's TRT Initial Panel is a blood test that requires clinician approval. After your initial screening, it can be scheduled through this portal and completed at a lab near you.
Visit Quest
Walk into a Quest Diagnostics location near you for a quick blood draw. For accurate assessment, this lab panel must be completed between 7:00 and 10:00 a.m., when testosterone levels are at their physiologic peak — tests drawn outside this window cannot be considered valid for treatment qualification. It is recommended to fast for at least 8 hours before.
Clinician review
Your results go directly to your clinician, who reviews them with you and determines whether TRT is appropriate. All results can be accessed through this portal.
What's included
- Lab requisition for Quest Diagnostics
- Comprehensive baseline hormone and safety markers
- Clinician review of your results
- Results available in your patient portal
Important to know
- Lab panels are ordered by a licensed clinician and drawn at Quest Diagnostics locations.
- This panel is required within six months prior to starting testosterone therapy (including testosterone injections, testosterone cream, hCG, and enclomiphene) to evaluate eligibility.
- A lab result alone is not a diagnosis; your clinician interprets results in the context of your health history.
- This is a one-time purchase, not a subscription.
